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It can be extremely difficult to tell if a mixed breed dog has a genetic tendency to develop a cardiovascular or nervous disorder. This is because most owners don’t know the exact breed makeup of their mixed breed, and genetic disorders are well linked to specific breeds.

Today, mixed breed Dog DNA tests can help erase that inequality. Mixed breed dog DNA tests can determine a mixed breed dog has a purebred parent or grandparent. Once you know the purebred makeup of your dog, your vet can determine if your dog is at risk of inheritied genetic disorders.

Inherited cardiovascular disorders include:

  • Aortic Stenosis
  • Atrial Septal Defect
  • Cardiomyopathy
  • Mitral Valve Dysplasia
  • Patent Ductus Arteriosus
  • Vascular Ring Anomaly
  • Portosystemic Shunt
  • Pulmonic Stenosis
  • Sick Sinus Syndrome
  • Tetralogy of Fallot
  • Tricuspid Dysplasia
  • Ventricular Septal Defect

Nervous disorders
Nervous system disorders are often seen in purebred dogs. They can occur in many purebred breeds, and are often difficult to diagnose and treat. Disorders of the nervous system of dogs, with an inherited component, include:

  • Cerebellar abiotrophy
  • Cerebellar hypoplasia
  • Cervical vertebral instability (Wobbler syndrome)
  • Congenital deafness and vestibular disease
  • Deafness
  • Degenerative myelopathy
  • Globoid cell leukodystrophy
  • Hypo-/dysmyelinogenesis
  • Hydrocephalus
  • Idiopathic epilepsy
  • Laryngeal paralysis
  • Leukodystrophies
  • Lissencephaly
  • Lysosomal storage diseases
  • Meningitis
  • Myasthenia gravis
  • Myelodysplasia
  • Neuroaxonal dystrophy
  • Peripheral neuropathies
  • Shaker dog syndrome
  • Scotty cramp
  • Spina bifida
  • Spinal muscular atrophy
  • Vertebral stenosis
Inherited Cardiovascular and Nervous Disorders in Mixed Breed Dogs